What is cytomegalovirus (CMV), and when should I seek advice?
What is cytomegalovirus (CMV)?
Cytomegalovirus (CMV) is a common virus that often causes no symptoms, but it deserves particular attention during pregnancy or when your immune system is weakened. If you are unwell, concerned about exposure or unsure what a result means, contact your GP or usual care team. Symptoms alone cannot tell you whether you have CMV.
Last updated 29 October 2026
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What symptoms can CMV cause?
Many people have no noticeable illness. When symptoms occur, they can include fever, a sore throat, swollen glands and tiredness. CDC information.
CMV can resemble glandular fever caused by Epstein–Barr virus. Assessment needs to consider other explanations, rather than assume CMV is the cause of a lingering illness. A GP may ask about the timing, examine you and decide which investigations would help. Victorian Department of Health.
Describe when symptoms began, whether they are improving and how they affect daily life. Bring up other changes even if they seem unrelated.
How does CMV spread?
CMV spreads through body fluids, including saliva, urine, semen, blood and breast milk. Young children can pass the virus in their saliva or urine while appearing well. Infection can pass to a developing baby during pregnancy. This is called congenital CMV, and differs from infection acquired after birth. Congenital infection can affect a child’s hearing or development, but not every baby with CMV develops health problems. CDC explanation.
Holding and cuddling a baby with CMV does not itself increase your risk. Sydney Children’s Hospitals Network.
How can I reduce exposure?
Wash hands after nappies, toileting and contact with saliva. Keep your eating utensils and drinks separate from young children’s, kiss them on the cheek or forehead instead of the lips, and clean contaminated toys and surfaces. NSW Health prevention advice.
Build the habits into routines with other carers. If you are pregnant, ask your maternity team about prevention even if a previous test showed past infection.
What changes during pregnancy?
Discuss CMV when planning a pregnancy or at an early antenatal appointment, especially if you regularly care for young children. You can raise prevention and testing even when you feel well.
A CMV IgG blood test looks for evidence that you have had CMV before. RANZCOG recommends offering it before or early in pregnancy to people with increased exposure, including parents of young children and early-childhood workers. It may also be offered to all pregnant people early in pregnancy with counselling, interpretation, follow-up and specialist pathways. Suspected new infection needs timely assessment and specialist advice. Current RANZCOG guidance.
If an infection is suspected, ask who will coordinate your next appointment and when you should expect contact. You do not have to work out a pregnancy management plan from an online result or leaflet.
What if my immune system is weakened?
People with weakened immunity, including some transplant recipients and people receiving cancer treatment, can develop more serious CMV illness. It may affect organs such as the eyes, lungs or gut. Victorian Department of Health.
Contact your treating team about new symptoms or an exposure concern, and use any instructions they have given you about fever or infection. Explain which treatment you receive and when your next dose or appointment is due. Do not stop or change immune-suppressing medicines yourself.
How are tests and results assessed?
A clinician chooses tests according to the question being asked: previous exposure, a possible recent illness, pregnancy concerns or illness during immune suppression. The type of test, its timing and your circumstances all matter when interpreting results. Victorian diagnostic guidance.
A single positive IgG result usually indicates previous infection. On its own, it cannot show when infection happened or whether a baby is infected. Previous infection does not completely protect against congenital CMV. Ask your clinician what your result means and what happens next. RANZCOG guidance.
Agree how and when you will receive an explanation. If a report arrives before your appointment, keep the full report, including its date and laboratory comments, for that discussion. A highlighted result is a reason to seek interpretation, rather than a complete diagnosis.
What helps with recovery and follow-up?
People with a healthy immune system who are not pregnant usually do not need specific CMV treatment. The virus stays in the body after infection and can reactivate; another strain can also cause reinfection. CDC overview.
Rest and fluids can help while recovering from a mild illness. Severe illness needs medical care. During pregnancy, with immune suppression or for a baby with congenital infection, the care team develops an individual plan. Sydney Children’s Hospitals Network.
If symptoms persist, worsen or return, arrange reassessment rather than assume the virus is responsible. Discuss work, caring responsibilities and how much activity you can manage. Ask what changes should bring your review forward.
When congenital CMV is diagnosed, a baby’s team arranges follow-up, including hearing and vision checks. CDC follow-up advice. Ask for the plan and contact details before leaving an appointment.
When should I seek urgent help?
During pregnancy, contact your doctor, midwife or maternity hospital immediately for fever or chills, bleeding, severe abdominal pain or reduced baby movements. These need assessment whatever the cause. Pregnancy warning signs.
If your immune system is weakened, follow your treating team’s urgent advice for new illness and seek urgent medical assessment for new vision problems. Call 000 for collapse, severe breathing difficulty or another life-threatening emergency. A phone discussion may need to be followed by an examination or hospital assessment.
What should I take to an appointment?
A short note is enough:
- When symptoms began and what has changed.
- Pregnancy stage or pregnancy plans, if relevant.
- Contact with young children at home or work, and your main concern.
- Medicines and treatments, including anything that affects immunity.
- Previous results, test dates and specialist letters, if available.
- Questions: What are we checking? Who will explain the result? When should I follow up? Who do I contact if I get worse?
Patient resources
- [Cerebral Palsy Alliance CMV resource hub](https://cerebralpalsy.org.au/our-research/cmv/cmv-resource-hub/) — pregnancy risk-reduction leaflets in English, Hindi, Arabic, Vietnamese and simplified and traditional Chinese; Aboriginal and Torres Strait Islander resources; pregnancy-diagnosis and postnatal-care pamphlets.
- [The CMV Association](https://www.cmv.org.au/) — family information and support resources.